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Protein folding in the periplasm in the absence of primary oxidant DsbA: modulation of redox potential in periplasmic space via OmpL porin

Disulfide bond formation in Escherichia coli is a catalyzed reaction accomplished by DsbA. We found that null mutations in a new porin gene, ompL, allowed a total bypass of the DsbA requirement for protein oxidation. These mutations acted as extragenic null suppressors for dsbA, and restored normal...

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Hlavní autoři: Dartigalongue, Claire, Nikaido, Hiroshi, Raina, Satish
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC305838/
https://ncbi.nlm.nih.gov/pubmed/11080145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.5980
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