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Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor
Latent signal transducers and activators of transcription (STATs) reside in the cytoplasm but rapidly accumulate in the nucleus following cytokine stimulation. Nuclear accumulation requires specific tyrosine phosphorylation and STAT dimerization. The presence of STATs in the nucleus is transient, ho...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305830/ https://ncbi.nlm.nih.gov/pubmed/11080165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.6196 |
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