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Cerebrospinal Fluid Profiles Predict Prospective Course and Outcome Among Persons with Amnestic Mild Cognitive Impairment

OBJECTIVES: To examine the effect of specific “CSF profiles” on the rate of cognitive decline, disease progression, and risk of conversion to Alzheimer's disease (AD) dementia in patients with amnestic mild cognitive impairment (MCI). DESIGN: Total tau (t-tau), tau phosphorylated at threonine 1...

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Autori principali: Okonkwo, Ozioma C., Mielke, Michelle M., Griffith, H. Randall, Moghekar, Abhay R., O'Brien, Richard J., Shaw, Leslie M., Trojanowski, John Q., Albert, Marilyn S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058271/
https://ncbi.nlm.nih.gov/pubmed/21220682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2010.334
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