P-SELECTIN MEDIATED PLATELET-NEUTROPHIL AGGREGATE FORMATION ACTIVATES NEUTROPHILS IN MOUSE AND HUMAN SICKLE CELL DISEASE

OBJECTIVE: Both platelet and neutrophil activation occur in sickle cell disease (SCD) but the interdependence of these events is unknown. The goal of this study was to determine the role of platelets in stimulating mouse and human neutrophil activation and pulmonary injury in SCD. METHODS AND RESULT...

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Detalhes bibliográficos
Main Authors: Polanowska-Grabowska, Renata, Wallace, Kori, Field, Joshua J., Chen, Lanlin, Marshall, Melissa A., Figler, Robert, Gear, Adrian R. L., Linden, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058044/
https://ncbi.nlm.nih.gov/pubmed/21071696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.211615
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