Calcium/Calmodulin Dependent Protein Kinase II Bound to NMDA Receptor 2B Subunit Exhibits Increased ATP Affinity and Attenuated Dephosphorylation

Calcium/calmodulin dependent protein kinase II (CaMKII) is implicated to play a key role in learning and memory. NR2B subunit of N-methyl-D-aspartate receptor (NMDAR) is a high affinity binding partner of CaMKII at the postsynaptic membrane. NR2B binds to the T-site of CaMKII and modulates its catal...

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Detalhes bibliográficos
Main Authors: Cheriyan, John, Kumar, Parimal, Mayadevi, Madhavan, Surolia, Avadhesha, Omkumar, Ramakrishnapillai V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057968/
https://ncbi.nlm.nih.gov/pubmed/21423658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016495
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