Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance

The 3′-azido-3′-deoxythymidine (AZT)-resistant pheno type of a heavily mutated human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) carrying a dipeptide (Ser-Ser) insertion between codons 69 and 70 as well as other mutations related to resistance to RT inhibitors has been studied....

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Bibliographic Details
Main Authors: Mas, Antonio, Parera, Mariona, Briones, Carlos, Soriano, Vicente, Martínez, Miguel Angel, Domingo, Esteban, Menéndez-Arias, Luis
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC305792/
https://ncbi.nlm.nih.gov/pubmed/11060026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.21.5752
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