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Modulation by Cytochrome P450-4A ω-Hydroxylase Enzymes of Adrenergic Vasoconstriction and Response to Reduced PO(2) in Mesenteric Resistance Arteries of Dahl Salt-Sensitive Rats

OBJECTIVE: This study evaluated the contribution of the 20-HETE/cytochrome P450-4A ω-hydroxylase (CYP4A) system to the early development of salt-induced vascular changes in Dahl salt-sensitive (SS) rats. METHODS: CYP4A expression and 20-HETE production were evaluated and responses to norepinephrine,...

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Main Authors: Raffai, Gábor, Wang, Jingli, Roman, Richard J., Anjaiah, Siddam, Weinberg, Brian, Falck, John R., Lombard, Julian H.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057905/
https://ncbi.nlm.nih.gov/pubmed/21040118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1549-8719.2010.00053.x
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