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Retinoid Signaling in Inner Ear Development: a “Goldilocks” Phenomenon

Retinoic acid is a biologically active derivative of vitamin A that is indispensable for inner ear development. The normal function of retinoic acid is achieved only at optimal homeostatic concentrations, with an excess or deficiency in retinoic acid leading to inner ear dysmorphogenesis. We present...

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Detalhes bibliográficos
Main Authors: Frenz, Dorothy A., Liu, Wei, Cvekl, Ales, Xie, Qing, Wassef, Lesley, Quadro, Loredana, Niederreither, Karen, Maconochie, Mark, Shanske, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057869/
https://ncbi.nlm.nih.gov/pubmed/21108385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.33670
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