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Dual Regulation of RA-RhoGAP Activity by Phosphatidic Acid and Rap1 during Neurite Outgrowth

During neurite outgrowth, Rho small G protein activity is spatiotemporally regulated to organize the neurite sprouting, extension, and branching. We have previously identified a potent Rho GTPase-activating protein (GAP), RA-RhoGAP, as a direct downstream target of Rap1 small G protein in the neurit...

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Bibliographic Details
Main Authors: Kurooka, Takao, Yamamoto, Yasunori, Takai, Yoshimi, Sakisaka, Toshiaki
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057846/
https://ncbi.nlm.nih.gov/pubmed/21169361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.183772
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