Amino Acids Activate Mammalian Target of Rapamycin Complex 2 (mTORC2) via PI3K/Akt Signaling

The activity of mammalian target of rapamycin (mTOR) complexes regulates essential cellular processes, such as growth, proliferation, or survival. Nutrients such as amino acids are important regulators of mTOR complex 1 (mTORC1) activation, thus affecting cell growth, protein synthesis, and autophag...

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Bibliographic Details
Main Authors: Tato, Irantzu, Bartrons, Ramon, Ventura, Francesc, Rosa, Jose Luis
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057817/
https://ncbi.nlm.nih.gov/pubmed/21131356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.166991
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