Structural Analysis of Mg(2+) and Ca(2+) Binding, Myristoylation, and Dimerization of the Neuronal Calcium Sensor and Visinin-like Protein 1 (VILIP-1)

Visinin-like protein 1 (VILIP-1) belongs to the neuronal calcium sensor family of Ca(2+)-myristoyl switch proteins that regulate signal transduction in the brain and retina. Here we analyze Ca(2+) and Mg(2+) binding, characterize metal-induced conformational changes, and determine structural effects...

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Hlavní autoři: Li, Congmin, Pan, Wensheng, Braunewell, Karl H., Ames, James B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057812/
https://ncbi.nlm.nih.gov/pubmed/21169352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.173724
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