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Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells.

Src homology domains [i.e., Src homology domain 2 (SH2) and Src homology domain 3 (SH3)] play a critical role in linking receptor tyrosine kinases to downstream signaling networks. A well-defined function of the SH3-SH2-SH3 adapter Grb2 is to link receptor tyrosine kinases, such as the epidermal gro...

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Dettagli Bibliografici
Autori principali: She, H Y, Rockow, S, Tang, J, Nishimura, R, Skolnik, E Y, Chen, M, Margolis, B, Li, W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC305731/
https://ncbi.nlm.nih.gov/pubmed/9307968
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