Stereo-selective inhibition of transient receptor potential TRPC5 cation channels by neuroactive steroids

BACKGROUND AND PURPOSE: Transient receptor potential canonical 5 (TRPC5) channels are widely expressed, including in the CNS, where they potentiate fear responses. They also contribute to other non-selective cation channels that are stimulated by G-protein-coupled receptor agonists and lipid and red...

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Bibliografiske detaljer
Main Authors: Majeed, Y, Amer, MS, Agarwal, AK, McKeown, L, Porter, KE, O'Regan, DJ, Naylor, J, Fishwick, CWG, Muraki, K, Beech, DJ
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2011
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057289/
https://ncbi.nlm.nih.gov/pubmed/21108630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01136.x
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