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Evidence that mating by the Saccharomyces cerevisiae gpa1Val50 mutant occurs through the default mating pathway and a suggestion of a role for ubiquitin-mediated proteolysis.

The yeast G alpha subunit, Gpa1p, plays a negative role in the pheromone response pathway. The gpa1Val50 mutant was previously shown to have a growth defect, consistent with the GTPase defect predicted for this mutation, and greatly reduced mating. Various explanations for the mating defect have bee...

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Publicat a:Mol Biol Cell
Autors principals: Xu, B E, Kurjan, J
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305726/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9307963/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.8.9.1649
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