Therapeutic benefits in thalassemic mice transplanted with long term cultured bone marrow cells

OBJECTIVE: Autologous bone marrow (BM) cells with a faulty gene corrected by gene targeting could provide a powerful therapeutic option for patients with genetic blood diseases. Achieving this goal is hindered by the low abundance of therapeutically useful BM cells and the difficulty of maintaining...

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Detalhes bibliográficos
Main Authors: Hatada, Seigo, Walton, William, Hatada, Tomoko, Wofford, Anne, Fox, Raymond, Liu, Naiyou, Lill, Michael C., Fair, Jeffery H., Kirby, Suzanne L., Smithies, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057214/
https://ncbi.nlm.nih.gov/pubmed/21184801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.12.007
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