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Dinoxin B, a Withanolide from Datura inoxia Leaves with Specific Cytotoxic Activities

A new withanolide, dinoxin B (12,21-dihydroxy-1-oxowitha-2,5,24-trienolide-27-O-β-d-glucopyranoside 1), was isolated from a methanol extract of Datura inoxia leaves, using bioassay-guided fractionation. The structure was determined by spectroscopic techniques, including (1)H, (13)C NMR, and 2D NMR e...

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Detalhes bibliográficos
Main Authors: Vermillion, Karl, Holguin, F. Omar, Berhow, Mark A., Richins, Richard D., Redhouse, Thurman, O’Connell, Mary A., Posakony, Jeff, Mahajan, Sumit S., Kelly, Sean M., Simon, Julian A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057138/
https://ncbi.nlm.nih.gov/pubmed/21280589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np1004714
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