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p53 Pro72Arg Polymorphism and Prostate Cancer in Men of African Descent

BACKGROUND: p53 is a transcription factor that regulates the cell cycle, DNA repair, and apoptosis. A variant at codon 72, rs1042522, results in altered activities for p53 and is, notably, differentially distributed among different ethnic populations. However, associations of this variant with cance...

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Main Authors: Ricks-Santi, L., Mason, T., Apprey, V., Ahaghotu, C., McLauchlin, A., Josey, D., Bonney, G., Dunston, G.M.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057117/
https://ncbi.nlm.nih.gov/pubmed/20593380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21209
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