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Molecular basis of differential sensitivity of insect sodium channels to DCJW, a bioactive metabolite of the oxadiazine insecticide indoxacarb

Indoxacarb (DPX-JW062) was recently developed as a new oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. Previous studies showed that indoxacarb and its bioactive metabolite, N-decarbomethoxyllated JW062 (DCJW), block insect sodium channels in nerve preparations and...

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Detalhes bibliográficos
Main Authors: Song, Weizhong, Liu, Zhiqi, Dong, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057067/
https://ncbi.nlm.nih.gov/pubmed/16325912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2005.10.004
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