Consumption of a High-Fat Diet Induces Central Insulin Resistance Independent of Adiposity

Plasma insulin enters the CNS where it interacts with insulin receptors in areas that are related to energy homeostasis and elicits a decrease of food intake and body weight. Here, we demonstrate that consumption of a high-fat (HF) diet impairs the central actions of insulin. Male Long-Evans rats we...

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Main Authors: Clegg, Deborah J., Gotoh, Koro, Kemp, Christopher, Wortman, Matthew D., Benoit, Stephen C., Brown, Lynda M., D’Alessio, David, Tso, Patrick, Seeley, Randy J., Woods, Stephen C.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056941/
https://ncbi.nlm.nih.gov/pubmed/21241723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physbeh.2011.01.010
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