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Lipophosphoglycan is not required for infection of macrophages or mice by Leishmania mexicana
Cell surface lipophosphoglycan (LPG) is commonly regarded as a multifunctional Leishmania virulence factor required for survival and development of these parasites in mammals. In this study, the LPG biosynthesis gene lpg1 was deleted in Leishmania mexicana by targeted gene replacement. The resulting...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2000
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305689/ https://ncbi.nlm.nih.gov/pubmed/10790362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.9.1953 |
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