Caricamento...

Epithelial Cell Stretching and Luminal Acidification Lead to a Retarded Development of Stria Vascularis and Deafness in Mice Lacking Pendrin

Loss-of-function mutations of SLC26A4/pendrin are among the most prevalent causes of deafness. Deafness and vestibular dysfunction in the corresponding mouse model, Slc26a4(−/−), are associated with an enlargement and acidification of the membranous labyrinth. Here we relate the onset of expression...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kim, Hyoung-Mi, Wangemann, Philine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056798/
https://ncbi.nlm.nih.gov/pubmed/21423764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017949
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !