G-CSF Prevents the Progression of Structural Disintegration of White Matter Tracts in Amyotrophic Lateral Sclerosis: A Pilot Trial

BACKGROUND: The hematopoietic protein Granulocyte-colony stimulating factor (G-CSF) has neuroprotective and -regenerative properties. The G-CSF receptor is expressed by motoneurons, and G-CSF protects cultured motoneuronal cells from apoptosis. It therefore appears as an attractive and feasible drug...

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Main Authors: Duning, Thomas, Schiffbauer, Hagen, Warnecke, Tobias, Mohammadi, Siawoosh, Floel, Agnes, Kolpatzik, Katja, Kugel, Harald, Schneider, Armin, Knecht, Stefan, Deppe, Michael, Schäbitz, Wolf Rüdiger
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056779/
https://ncbi.nlm.nih.gov/pubmed/21423758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017770
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