In vitro evaluation of a double-stranded self-complementary adeno-associated virus type2 vector in bone marrow stromal cells for bone healing

BACKGROUND: Both adenoviral and lentiviral vectors have been successfully used to induce bone repair by over-expression of human bone morphogenetic protein 2 (BMP-2) in primary rat bone marrow stromal cells in pre-clinical models of ex vivo regional gene therapy. Despite being a very efficient means...

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Autors principals: Alaee, Farhang, Sugiyama, Osamu, Virk, Mandeep S, Tang, Ying, Wang, Bing, Lieberman, Jay R
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056728/
https://ncbi.nlm.nih.gov/pubmed/21352585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-9-4
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