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Rare and Frequent Promoter Methylation, Respectively, of TSHZ2 and 3 Genes That Are Both Downregulated in Expression in Breast and Prostate Cancers

BACKGROUND: Neoplastic cells harbor both hypomethylated and hypermethylated regions of DNA. Whereas hypomethylation is found mainly in repeat sequences, regional hypermethylation has been linked to the transcriptional silencing of certain tumor suppressor genes. We attempted to search for candidate...

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Hlavní autoři: Yamamoto, Miyako, Cid, Emili, Bru, Samuel, Yamamoto, Fumiichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056709/
https://ncbi.nlm.nih.gov/pubmed/21423795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017149
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