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Escherichia coli promoter opening and −10 recognition: mutational analysis of σ70

The opening of specific segments of DNA is required for most types of genetic readout, including σ70-dependent transcription. To learn how this occurs, a series of single point mutations were introduced into σ70 region 2. These were assayed for duplex DNA binding, DNA opening and DNA double strand–s...

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Bibliografiske detaljer
Main Authors: Fenton, Mike S., Lee, Shun Jin, Gralla, Jay D.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC305651/
https://ncbi.nlm.nih.gov/pubmed/10698953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.5.1130
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