Seizure Outcomes Following Use of Generic vs. Brand-Name Antiepileptic Drugs: A Systematic Review and Meta-Analysis

BACKGROUND: The automatic substitution of bioequivalent generic for brand-name antiepileptic drugs (AEDs) has been linked by anecdotal report to loss of seizure control. OBJECTIVE: To evaluate studies comparing brand-name and generic AEDs and determine whether evidence exists of superiority of the b...

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Autori principali: Kesselheim, Aaron S., Stedman, Margaret R., Bubrick, Ellen J., Gagne, Joshua J., Misono, Alexander S., Lee, Joy L., Brookhart, M. Alan, Avorn, Jerry, Shrank, William H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056509/
https://ncbi.nlm.nih.gov/pubmed/20329806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2165/10898530-000000000-00000
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