Defining the role of a FYVE domain in the localization and activity of a cAMP phosphodiesterase implicated in osmoregulation in Trypanosoma cruzi

Intracellular levels of cyclic nucleotide second messengers are regulated predominantly by a large superfamily of phosphodiesterases. Trypanosoma cruzi, the causative agent of Chagas disease, encodes four different phosphodiesterase (PDE) families. One of these PDEs, T. cruzi phosphodiesterase C2 (T...

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Bibliografiske detaljer
Main Authors: Schoijet, Alejandra C., Miranda, Kildare, Medeiros, Lia Carolina Soares, de Souza, Wanderley, Flawiá, Mirtha M., Torres, Héctor N., Pignataro, Omar P., Docampo, Roberto, Alonso, Guillermo D.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056490/
https://ncbi.nlm.nih.gov/pubmed/21166893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07429.x
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