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Charged tmRNA but not tmRNA-mediated proteolysis is essential for Neisseria gonorrhoeae viability

tmRNA, through its tRNA and mRNA properties, adds short peptide tags to abnormal proteins, targeting these proteins for proteolytic degradation. Although the conservation of tmRNA throughout the bacterial kingdom suggests that it must provide a strong selective advantage, it has not been shown to be...

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Autori principali: Huang, Canhui, Wolfgang, Matthew C., Withey, Jeffrey, Koomey, Michael, Friedman, David I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC305648/
https://ncbi.nlm.nih.gov/pubmed/10698950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.5.1098
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