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LASTING EPIGENETIC INFLUENCE OF EARLY-LIFE ADVERSITY ON THE BDNF GENE

BACKGROUND: Childhood maltreatment and early trauma leave lasting imprints on neural mechanisms of cognition and emotion. Using a rat model of infant maltreatment by a caregiver, we investigated whether early-life adversity leaves lasting epigenetic marks at the Brain-derived Neurotrophic Factor (BD...

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Detalhes bibliográficos
Main Authors: Roth, Tania L., Lubin, Farah D., Funk, Adam J., Sweatt, J. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056389/
https://ncbi.nlm.nih.gov/pubmed/19150054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.11.028
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