Inhibition of Epithelial Mesenchymal Transition (EMT) With Immunochemogene Treatment in Metastatic Colorectal Cancer

BACKGROUND: Epithelial to mesenchymal transition (EMT) causes resistance to epidermal growth factor receptor (EGFR) inhibitors. We used immunochemogene treatment composed of a stealth nanoparticle formulation, consisting of clamp PNA against mRNA of FOXC2, anti-CD44 chimeric MAb, and vinorelbine, in...

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Main Authors: Giannios, John, Michailakis, Emmanuel, Papanikolaou, John, Alexandropoulos, Nick
Format: Artigo
Language:Inglês
Published: International Society of Gastrointestinal Oncology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056306/
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