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Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM

Major histocompatibility complex (MHC) class II molecules bind and present to CD4(+) T cells peptides derived from endocytosed antigens. Class II molecules associate in the endoplasmic reticulum with invariant chain (Ii), which (i) mediates the delivery of the class II–Ii complexes into the endocyti...

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Autors principals: Villadangos, José A., Driessen, Christoph, Shi, Guo-Ping, Chapman, Harold A., Ploegh, Hidde L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC305628/
https://ncbi.nlm.nih.gov/pubmed/10698930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.5.882
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