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Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM

Major histocompatibility complex (MHC) class II molecules bind and present to CD4(+) T cells peptides derived from endocytosed antigens. Class II molecules associate in the endoplasmic reticulum with invariant chain (Ii), which (i) mediates the delivery of the class II–Ii complexes into the endocyti...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Villadangos, José A., Driessen, Christoph, Shi, Guo-Ping, Chapman, Harold A., Ploegh, Hidde L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305628/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10698930/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.5.882
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