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Lack of PPARα exacerbates lipopolysaccharide-induced liver toxicity through STAT1 inflammatory signaling and increased oxidative/nitrosative stress,

Peroxisome proliferator-activated receptor-α (PPARα) has been implicated in a potent anti-inflammatory activity. However, no information is available on whether PPARα can affect signal transducers and activator of transcription proteins (STATs) in acute liver damage. Thus, this study was aimed to in...

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Autors principals: Yoo, Seong Ho, Park, Ogyi, Henderson, Lauren E., Abdelmegeed, Mohamed A., Moon, Kwan-Hoon, Song, Byoung-Joon
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056153/
https://ncbi.nlm.nih.gov/pubmed/21262334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2011.01.013
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