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A single point mutation in TFIIA suppresses NC2 requirement in vivo
Negative cofactor 2 (NC2) is a dimeric histone-fold complex that represses RNA polymerase II transcription through binding to TATA-box-binding protein (TBP) and inhibition of the general transcription factors TFIIA and TFIIB. Here we study molecular mechanisms of repression by human NC2 in vivo in y...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305605/ https://ncbi.nlm.nih.gov/pubmed/10675336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.672 |
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