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N-acyl homoserine lactone binding to the CarR receptor determines quorum-sensing specificity in Erwinia

Quorum sensing via an N–acyl homoserine lactone (HSL) pheromone controls the biosynthesis of a carbapenem antibiotic in Erwinia carotovora. Transcription of the carbapenem biosynthetic genes is dependent on the LuxR-type activator protein, CarR. Equilibrium binding of a range of HSL molecules, which...

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Main Authors: Welch, Martin, Todd, Daniel E., Whitehead, Neil A., McGowan, Simon J., Bycroft, Barrie W., Salmond, George P.C.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC305601/
https://ncbi.nlm.nih.gov/pubmed/10675332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.631
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