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PrtT-Regulated Proteins Secreted by Aspergillus fumigatus Activate MAPK Signaling in Exposed A549 Lung Cells Leading to Necrotic Cell Death

Aspergillus fumigatus is the most commonly encountered mold pathogen of humans, predominantly infecting the respiratory system. Colonization and penetration of the lung alveolar epithelium is a key but poorly understood step in the infection process. This study focused on identifying the transcripti...

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Библиографические подробности
Главные авторы: Sharon, Haim, Amar, David, Levdansky, Emma, Mircus, Gabriel, Shadkchan, Yana, Shamir, Ron, Osherov, Nir
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055868/
https://ncbi.nlm.nih.gov/pubmed/21412410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017509
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