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A small amphipathic α-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5
Cytokines induce the tyrosine phosphorylation and associated activation of signal transducers and acti– vators of transcription (Stat). The mechanisms by which this response is terminated are largely unknown. Among a variety of inhibitors examined, the proteasome inhibitors MG132 and lactacystin aff...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305576/ https://ncbi.nlm.nih.gov/pubmed/10654938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.3.392 |
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