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Identification of the Raf-1 Signaling Pathway Used by cAMP to Inhibit p42/p44 MAPK in Rat Lacrimal Gland Acini: Role in Potentiation of Protein Secretion

PURPOSE. The lacrimal gland is primarily responsible for the aqueous portion of the tear film. Simultaneous addition of cholinergic agonists or growth factors with cAMP-dependent agonists potentiates secretion. Recent investigations revealed that cAMP decreases p44/p42 mitogen-activated protein kina...

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Detalhes bibliográficos
Main Authors: Funaki, Chika, Hodges, Robin R., Dartt, Darlene A.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055758/
https://ncbi.nlm.nih.gov/pubmed/20671279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5690
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