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Stress-Hyperresponsive WKY Rats Demonstrate Depressed Dorsal Raphe Neuronal Excitability and Dysregulated CRF-Mediated Responses

Major depression is a debilitating psychiatric disease that may be precipitated by a dysregulation of stress neurocircuitry caused by chronic or severe stress exposure. Moreover, hyperresponsivity to stressors correlates with depressed mood and may contribute to the etiology of major depression. The...

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Main Authors: Lemos, Julia C, Zhang, Guojun, Walsh, Teresa, Kirby, Lynn G, Akanwa, Adaure, Brooks-Kayal, Amy, Beck, Sheryl G
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055727/
https://ncbi.nlm.nih.gov/pubmed/21160465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.200
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