Epistasis of the DRD2/ANKK1 Taq Ia and the BDNF Val66Met Polymorphism Impacts Novelty Seeking and Harm Avoidance

Mounting evidence from animal studies show that the mesolimbic dopaminergic pathways are modulated by the brain-derived neurotrophic factor (BDNF). This study investigates in N=768 healthy Caucasian participants the influence of two prominent functional single-nucleotide polymorphisms (SNPs) on the...

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Autori principali: Montag, Christian, Markett, Sebastian, Basten, Ulrike, Stelzel, Christine, Fiebach, Christian, Canli, Turhan, Reuter, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055626/
https://ncbi.nlm.nih.gov/pubmed/20410875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.55
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