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Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30) complex
Saccharomyces cerevisiae SCF(Met30) ubiquitin–protein ligase controls cell cycle function and sulfur amino acid metabolism. We report here that the SCF(Met30) complex mediates the transcriptional repression of the MET gene network by triggering degradation of the transcriptional activator Met4p when...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305562/ https://ncbi.nlm.nih.gov/pubmed/10637232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.2.282 |
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