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The PTPN22*C1858T functional polymorphism is associated with susceptibility to inflammatory polyarthritis but neither this nor other variants spanning the gene is associated with disease outcome

BACKGROUND: The PTPN22 gene has been widely confirmed as a susceptibility gene for rheumatoid arthritis (RA) in populations of Northern European descent. The aim of the current study was to explore the role of variants spanning the PTPN22 gene in determining susceptibility to and outcome of inflamma...

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Detalhes bibliográficos
Main Authors: Naseem, H, Thomson, W, Silman, A, Worthington, J, Symmons, D, Barton, A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055597/
https://ncbi.nlm.nih.gov/pubmed/17666450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2007.071894
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