Interleukin-1 Receptor Activation by Systemic Lipopolysaccharide Induces Behavioral Despair Linked to MAPK Regulation of CNS Serotonin Transporters

Serotonin (5-hydroxytryptamine, 5-HT) has long been implicated in regulation of mood. Medications that block the neuronal 5-HT transporter (SERT) are used as major pharmacological treatment for mood disorders. Conversely, stimuli that enhance SERT activity might be predicted to diminish synaptic 5-H...

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Detalhes bibliográficos
Main Authors: Zhu, Chong-Bin, Lindler, Kathryn M, Owens, Anthony W, Daws, Lynette C, Blakely, Randy D, Hewlett, William A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055584/
https://ncbi.nlm.nih.gov/pubmed/20827273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.116
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