Association of SOD2, a Mitochondrial Antioxidant Enzyme, with Gray Matter Volume Shrinkage in Alcoholics

Chronic alcoholism leads to gray matter shrinkage and induces the formation of superoxide anions (O(2)(−)) that can cause neuronal cell death. The mitochondrial superoxide dismutase 2 (SOD2) enzyme is critical in the metabolism of superoxide. An Ala16Val polymorphism putatively affects SOD2 enzyme a...

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Autori principali: Srivastava, Vibhuti, Buzas, Beata, Momenan, Reza, Oroszi, Gabor, Pulay, Attila J, Enoch, Mary-Anne, Hommer, Daniel W, Goldman, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055396/
https://ncbi.nlm.nih.gov/pubmed/20043000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.217
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