Genetic Deletion of Fatty Acid Amide Hydrolase Alters Emotional Behavior and Serotonergic Transmission in the Dorsal Raphe, Prefrontal Cortex, and Hippocampus

Pharmacological blockade of the anandamide-degrading enzyme, fatty acid amide hydrolase (FAAH), produces CB(1) receptor (CB(1)R)-mediated analgesic, anxiolytic-like and antidepressant-like effects in murids. Using behavioral and electrophysiological approaches, we have characterized the emotional ph...

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Main Authors: Bambico, Francis Rodriguez, Cassano, Tommaso, Dominguez-Lopez, Sergio, Katz, Noam, Walker, Claire Dominique, Piomelli, Daniele, Gobbi, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055302/
https://ncbi.nlm.nih.gov/pubmed/20571484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.80
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