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p21 expression and mutation in gastric carcinoma: analysis by immunohistochemistry and PCR-SSCP.

p21 protein has been reported to be a critical downstream effector of p53 and a potent inhibitor of cyclin-dependent kinases. Thus, the p21 gene is thought to play a central role in tumor suppression. In this study we investigated p21 protein expression and mutation in gastric adenocarcinoma. A tota...

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Detalhes bibliográficos
Main Authors: Park, Y. E., Choi, K. C., Choi, Y. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Academy of Medical Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3054511/
https://ncbi.nlm.nih.gov/pubmed/9811180
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