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Periplasmic vestibule plays an important role for solute recruitment, selectivity, and gating in the Rh/Amt/MEP superfamily

AmtB, a member of the Rh/Amt/MEP superfamily, is responsible for ammonia transport in Escherichia coli. The ammonia pathway in AmtB consists of a narrow hydrophobic lumen in between hydrophilic periplasmic and cytoplasmic vestibules. A series of molecular dynamics simulations (greater than 0.4 μs in...

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Detalhes bibliográficos
Main Authors: Akgun, Ugur, Khademi, Shahram
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3054019/
https://ncbi.nlm.nih.gov/pubmed/21368153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007240108
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