Snapin Mediates Incretin Action And Augments Glucose-dependent Insulin Secretion

Impaired insulin secretion contributes to the pathogenesis of type 2 diabetes mellitus (T2DM). Treatment with the incretin hormone glucagon like peptide-1 (GLP-1) potentiates insulin secretion and improves metabolic control in humans with T2DM. GLP-1 receptor-mediated signaling leading to insulin se...

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Détails bibliographiques
Auteurs principaux: Song, Woo-Jin, Seshadri, Madhav, Ashraf, Uzair, Mdluli, Thembi, Mondal, Prosenjit, Keil, Meg, Azevedo, Monalisa, Kirschner, Lawrence S., Stratakis, Constantine A., Hussain, Mehboob A.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053597/
https://ncbi.nlm.nih.gov/pubmed/21356520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.02.002
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