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TRPV1 Activation Is Required for Hypertonicity-Stimulated Inflammatory Cytokine Release in Human Corneal Epithelial Cells

PURPOSE. To determine whether hypertonic stress promotes increases in inflammatory cytokine release through transient receptor potential vanilloid channel type 1 (TRPV1) signaling pathway activation in human corneal epithelial cells (HCECs). METHODS. Hyperosmotic medium was prepared by supplementing...

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Detalhes bibliográficos
Main Authors: Pan, Zan, Wang, Zheng, Yang, Hua, Zhang, Fan, Reinach, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053292/
https://ncbi.nlm.nih.gov/pubmed/20739465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5801
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