Neutron fibre diffraction studies of amyloid using H(2)O/D(2)O isotopic replacement

The first neutron fibre diffraction studies of an amyloid system are presented. The techniques used to prepare the large samples needed are described, as well as the procedures used to isotopically replace H(2)O in the sample by D(2)O. The results demonstrate the feasibility of this type of approach...

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Bibliographic Details
Main Authors: Tiggelaar, Sarah M., Mossou, Estelle, Callow, Phil, Callow, Shirley, Teixeira, Susana C. M., Mitchell, Edward P., Mitraki, Anna, Forsyth, V. Trevor
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2011
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053157/
https://ncbi.nlm.nih.gov/pubmed/21393837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111002351
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