Neutron fibre diffraction studies of amyloid using H(2)O/D(2)O isotopic replacement

The first neutron fibre diffraction studies of an amyloid system are presented. The techniques used to prepare the large samples needed are described, as well as the procedures used to isotopically replace H(2)O in the sample by D(2)O. The results demonstrate the feasibility of this type of approach...

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Detalhes bibliográficos
Main Authors: Tiggelaar, Sarah M., Mossou, Estelle, Callow, Phil, Callow, Shirley, Teixeira, Susana C. M., Mitchell, Edward P., Mitraki, Anna, Forsyth, V. Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Crystallization Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053157/
https://ncbi.nlm.nih.gov/pubmed/21393837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111002351
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