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Dyskinesias Do Not Develop after Chronic Intermittent Levodopa Therapy in Clinically Hemiparkinsonian Rhesus Monkeys

The stable 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian (HP) rhesus monkey model of Parkinson’s disease (PD) has been frequently used to test preclinical experimental therapeutics targeted to treat patients with advanced PD who suffer from motor fluctuations and drug-...

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Detalhes bibliográficos
Main Authors: Lieu, Christopher A., Deogaonkar, Milind, Bakay, Roy A. E., Subramanian, Thyagarajan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053121/
https://ncbi.nlm.nih.gov/pubmed/21074478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2010.10.010
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